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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2005-7-25
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pubmed:abstractText |
Interleukin-1 beta (IL-1beta) has been implicated as an extracellular signal in the initiation of apoptosis in neurons and oligodendrocytes after spinal cord injury (SCI). To further characterize the apoptotic cascade initiated by IL-1beta after SCI, we examined the expression of IL-1beta, p38 mitogen-activated protein kinase (p38 MAPK) and caspase-3 after SCI, and further investigated whether p38 MAPK was involved in neuron apoptosis induced by IL-1beta.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Casp3 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Caspases,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin 1 Receptor Antagonist...,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/SB 203580,
http://linkedlifedata.com/resource/pubmed/chemical/Sialoglycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1671-4083
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
934-42
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16038625-Animals,
pubmed-meshheading:16038625-Apoptosis,
pubmed-meshheading:16038625-Blotting, Western,
pubmed-meshheading:16038625-Caspase 3,
pubmed-meshheading:16038625-Caspases,
pubmed-meshheading:16038625-Enzyme Activation,
pubmed-meshheading:16038625-Enzyme Inhibitors,
pubmed-meshheading:16038625-Gene Expression,
pubmed-meshheading:16038625-Imidazoles,
pubmed-meshheading:16038625-Immunohistochemistry,
pubmed-meshheading:16038625-In Situ Nick-End Labeling,
pubmed-meshheading:16038625-Interleukin 1 Receptor Antagonist Protein,
pubmed-meshheading:16038625-Interleukin-1,
pubmed-meshheading:16038625-Male,
pubmed-meshheading:16038625-Neurons,
pubmed-meshheading:16038625-Pyridines,
pubmed-meshheading:16038625-RNA, Messenger,
pubmed-meshheading:16038625-Rats,
pubmed-meshheading:16038625-Rats, Wistar,
pubmed-meshheading:16038625-Receptors, Interleukin-1,
pubmed-meshheading:16038625-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16038625-Sialoglycoproteins,
pubmed-meshheading:16038625-Spinal Cord Injuries,
pubmed-meshheading:16038625-Time Factors,
pubmed-meshheading:16038625-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2005
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pubmed:articleTitle |
Interleukin-1 beta induction of neuron apoptosis depends on p38 mitogen-activated protein kinase activity after spinal cord injury.
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pubmed:affiliation |
Department of Spine Surgery, The Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China. xj.wang2000@163.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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