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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-7-13
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pubmed:abstractText |
We performed a clinical study to confirm whether and how residual lens epithelial cells (LECs) participate in postoperative pseudophakic inflammation, including fibrin reaction. Twenty-six eyes of 13 patients with bilateral cataracts were treated by phacoemulsification and posterior chamber intraocular lens (PC-IOL) implantation. In the eye from which LECs had not been removed, the aqueous flare was measured with a laser flare-cell meter. Flare decreased from an initial peak, increasing again to form a flare spike when LECs came into contact with the PC-IOL and began to undergo fibrous proliferation at 6 to 14 days after surgery. The spike was evidence that the blood-aqueous barrier had been disrupted again. Fibrin reaction developed in two eyes. In the other eye of each pair, from which LECs had been removed by ultrasound aspiration, neither a flare spike nor fibrous proliferation was noted. We conclude that residual LECs break down the blood-aqueous barrier as they proliferate and are involved in postoperative pseudophakic inflammation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-023X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
325-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1603532-Adult,
pubmed-meshheading:1603532-Aged,
pubmed-meshheading:1603532-Aqueous Humor,
pubmed-meshheading:1603532-Biological Transport, Active,
pubmed-meshheading:1603532-Blood,
pubmed-meshheading:1603532-Cataract Extraction,
pubmed-meshheading:1603532-Endophthalmitis,
pubmed-meshheading:1603532-Epithelium,
pubmed-meshheading:1603532-Female,
pubmed-meshheading:1603532-Humans,
pubmed-meshheading:1603532-Lens, Crystalline,
pubmed-meshheading:1603532-Lens Diseases,
pubmed-meshheading:1603532-Lenses, Intraocular,
pubmed-meshheading:1603532-Male,
pubmed-meshheading:1603532-Middle Aged,
pubmed-meshheading:1603532-Postoperative Complications
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pubmed:year |
1992
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pubmed:articleTitle |
Disruption of the blood-aqueous barrier by residual lens epithelial cells after intraocular lens implantation.
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pubmed:affiliation |
Nishi Eye Hospital, Osaka, Japan.
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pubmed:publicationType |
Journal Article
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