Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-7-27
pubmed:abstractText
In studies from several laboratories using a variety of different techniques, features of the zygote and two-cell conceptus have been found to map nonrandomly on the blastocyst with respect to both its axis of polarity and bilateral plane. This is not what would be expected if, as is widely believed, early patterning depends entirely on positional relationships and interactions among the progeny of blastomeres that are equipotential until at least the eight-cell stage. Rather, the implication of these findings is that prepatterning is a normal facet of development in mammals, just as it is in most other metazoa. Nevertheless, there is still no general consensus regarding the extent to which such prepatterning depends on intrinsic organization of the oocyte, as opposed to events that are contingent on fertilization.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1542-975X
pubmed:author
pubmed:copyrightInfo
(c) 2005 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
142-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The case for prepatterning in the mouse.
pubmed:affiliation
Mammalian Development Laboratory, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom. richard.gardner@zoology.ox.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't