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pubmed-article:16033846pubmed:abstractTextTopical application of the immune response modifier imiquimod is an alternative approach for the treatment of human papillomavirus (HPV)-positive vulvar intraepithelial neoplasia (VIN) and aims at the immunologic eradication of HPV-infected cells. We have charted HPV16-specific immunity in 29 patients with high-grade VIN and examined its role in the clinical effect of imiquimod treatment.lld:pubmed
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pubmed-article:16033846pubmed:articleTitleDetection of human papillomavirus (HPV) 16-specific CD4+ T-cell immunity in patients with persistent HPV16-induced vulvar intraepithelial neoplasia in relation to clinical impact of imiquimod treatment.lld:pubmed
pubmed-article:16033846pubmed:affiliationDepartment of Gynecology, Leiden University Medical Center, Leiden, The Netherlands.lld:pubmed
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