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rdf:type |
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lifeskim:mentions |
umls-concept:C0020964,
umls-concept:C0021344,
umls-concept:C0030705,
umls-concept:C0080103,
umls-concept:C0087111,
umls-concept:C0165032,
umls-concept:C0205210,
umls-concept:C0205322,
umls-concept:C0346210,
umls-concept:C1332714,
umls-concept:C1511790
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|
pubmed:issue |
14
|
|
pubmed:dateCreated |
2005-7-21
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|
pubmed:abstractText |
Topical application of the immune response modifier imiquimod is an alternative approach for the treatment of human papillomavirus (HPV)-positive vulvar intraepithelial neoplasia (VIN) and aims at the immunologic eradication of HPV-infected cells. We have charted HPV16-specific immunity in 29 patients with high-grade VIN and examined its role in the clinical effect of imiquimod treatment.
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pubmed:language |
eng
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|
pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
pubmed-author:DrijfhoutJan WJW,
pubmed-author:Heijmans-AntonissenClaudiaC,
pubmed-author:HelmerhorstTheo J MTJ,
pubmed-author:KenterGemma GGG,
pubmed-author:KwappenbergKitty M CKM,
pubmed-author:MeliefCornelis J MCJ,
pubmed-author:OffringaRienkR,
pubmed-author:van BeurdenMarcM,
pubmed-author:van PoelgeestMariëtte I EMI,
pubmed-author:van SetersManonM,
pubmed-author:van der BurgSjoerd HSH
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|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
5273-80
|
|
pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16033846-Adjuvants, Immunologic,
pubmed-meshheading:16033846-Adult,
pubmed-meshheading:16033846-Aged,
pubmed-meshheading:16033846-Aminoquinolines,
pubmed-meshheading:16033846-CD4-Positive T-Lymphocytes,
pubmed-meshheading:16033846-Carcinoma in Situ,
pubmed-meshheading:16033846-Female,
pubmed-meshheading:16033846-Humans,
pubmed-meshheading:16033846-Immunity, Cellular,
pubmed-meshheading:16033846-Interferon-gamma,
pubmed-meshheading:16033846-Middle Aged,
pubmed-meshheading:16033846-Papillomaviridae,
pubmed-meshheading:16033846-Treatment Outcome,
pubmed-meshheading:16033846-Vulvar Neoplasms
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Detection of human papillomavirus (HPV) 16-specific CD4+ T-cell immunity in patients with persistent HPV16-induced vulvar intraepithelial neoplasia in relation to clinical impact of imiquimod treatment.
|
|
pubmed:affiliation |
Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
