Source:http://linkedlifedata.com/resource/pubmed/id/16029352
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2005-7-20
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pubmed:abstractText |
Existing systemic treatments for New World cutaneous leishmaniasis (CL) caused by Leishmania (vianna) braziliensis are unsatisfactory. Liposomal amphotericin B has been used extensively for the treatment of visceral leishmaniasis, but in few cases of CL, and an appropriate regimen for CL has not been described. We successfully treated a patient with multiple L. braziliensis CL lesions acquired in Belize. Liposomal amphotericin B (AmBisome) was given to our patient as an inpatient for seven daily doses of 3 mg kg(-1) day(-1) and then as an outpatient at 3 mg kg(-1) twice weekly for a further three weeks, a total of 40 mg kg(-1). Liposomal amphotericin offers a well-tolerated alternative to pentavalent antimony or amphotericin B deoxycholate for the systemic treatment of New World CL.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
153
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-5
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pubmed:meshHeading |
pubmed-meshheading:16029352-Adult,
pubmed-meshheading:16029352-Amphotericin B,
pubmed-meshheading:16029352-Animals,
pubmed-meshheading:16029352-Antiprotozoal Agents,
pubmed-meshheading:16029352-Humans,
pubmed-meshheading:16029352-Leg Dermatoses,
pubmed-meshheading:16029352-Leishmania braziliensis,
pubmed-meshheading:16029352-Leishmaniasis, Cutaneous,
pubmed-meshheading:16029352-Liposomes,
pubmed-meshheading:16029352-Male
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pubmed:year |
2005
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pubmed:articleTitle |
Successful liposomal amphotericin B treatment of Leishmania braziliensis cutaneous leishmaniasis.
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pubmed:affiliation |
Department of Infection & Tropical Medicine, Northwick Park Hospital, Harrow, UK. michael.brown@lshtm.ac.uk
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pubmed:publicationType |
Journal Article,
Case Reports
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