Source:http://linkedlifedata.com/resource/pubmed/id/16026902
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2006-4-18
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pubmed:abstractText |
Several studies have reported conflicting results concerning the genetic association between Alzheimer's disease (AD) and the microsatellite marker D10S1423 on chromosome 10p12-14. In an ethnically homogeneous German population of 422 patients with AD and 254 cognitively healthy controls, the 238-bp allele of the D10S1423 marker showed a weak, but after correction for multiple testing no longer significant association with AD (p = 0.015, uncorrected; p = 0.11, corrected). These findings do not support the presence of a relevant susceptibility locus for AD on chromosome 10p12-14.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1558-1497
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
776.e1-776.e3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16026902-Aged,
pubmed-meshheading:16026902-Alleles,
pubmed-meshheading:16026902-Alzheimer Disease,
pubmed-meshheading:16026902-Apolipoprotein E4,
pubmed-meshheading:16026902-Apolipoproteins E,
pubmed-meshheading:16026902-Chromosomes, Human, Pair 10,
pubmed-meshheading:16026902-Cohort Studies,
pubmed-meshheading:16026902-Female,
pubmed-meshheading:16026902-Gene Frequency,
pubmed-meshheading:16026902-Germany,
pubmed-meshheading:16026902-Humans,
pubmed-meshheading:16026902-Male,
pubmed-meshheading:16026902-Microsatellite Repeats
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pubmed:year |
2006
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pubmed:articleTitle |
Association study between the D10S1423 microsatellite marker and Alzheimer's disease.
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pubmed:affiliation |
Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universität München (TUM), Ismaningerstr. 22, D-81675 Munich, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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