rdf:type |
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lifeskim:mentions |
umls-concept:C0023089,
umls-concept:C0031809,
umls-concept:C0034378,
umls-concept:C0037813,
umls-concept:C0332306,
umls-concept:C0456644,
umls-concept:C0596801,
umls-concept:C1511726,
umls-concept:C1537055,
umls-concept:C1555977,
umls-concept:C1825291,
umls-concept:C2610507
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pubmed:dateCreated |
2005-7-19
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pubmed:abstractText |
Proteomic profiling of complex biological mixtures by the ProteinChip technology of surface-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectrometry (MS) is one of the most promising approaches in toxicological, biological, and clinic research. The reliable identification of protein expression patterns and associated protein biomarkers that differentiate disease from health or that distinguish different stages of a disease depends on developing methods for assessing the quality of SELDI-TOF mass spectra. The use of SELDI data for biomarker identification requires application of rigorous procedures to detect and discard low quality spectra prior to data analysis.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-10786889,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-12298096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-12324514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-12781425,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-12925511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-14500586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-14523236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-14583499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15014013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15020796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15112261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15253447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15264244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15274357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15283893,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15351507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15352246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16026602-15450932
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1471-2105
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
6 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
2005
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pubmed:articleTitle |
Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).
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pubmed:affiliation |
Division of Bioinformatics, Z-Tech at FDA's National Center for Toxicological Research, Jefferson, Arkansas 72079, USA. hhong@nctr.fda.gov
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pubmed:publicationType |
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, N.I.H., Extramural,
Addresses,
Validation Studies
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