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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0009429,
umls-concept:C0033684,
umls-concept:C0376705,
umls-concept:C0444669,
umls-concept:C0449774,
umls-concept:C0525038,
umls-concept:C0556895,
umls-concept:C0871261,
umls-concept:C1148363,
umls-concept:C1533728,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
6
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pubmed:dateCreated |
2005-7-18
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pubmed:abstractText |
Patients with high titer (>/=100 kIU/ml) of hepatitis C virus (HCV) genotype 1b do not achieve highly sustained virological response rates to combination therapy with interferon plus ribavirin. Non-virological responders (NVRs, namely ultimate resistant cases) who do not achieve HCV-RNA negativity during treatment are also encountered. We investigated the pretreatment virological features of NVRs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antiviral Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Interferons,
http://linkedlifedata.com/resource/pubmed/chemical/NS-5 protein, hepatitis C virus,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Ribavirin,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Core Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Nonstructural Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/nucleocapsid protein, Hepatitis C...
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pubmed:status |
MEDLINE
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pubmed:issn |
0300-5526
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pubmed:author |
pubmed-author:AkutaNorioN,
pubmed-author:AraseYasujiY,
pubmed-author:HosakaTetsuyaT,
pubmed-author:IkedaKenjiK,
pubmed-author:KobayashiMarikoM,
pubmed-author:KobayashiMasahiroM,
pubmed-author:KumadaHiromitsuH,
pubmed-author:MatsudaMarieM,
pubmed-author:SaitohSatoshiS,
pubmed-author:SatoJunkoJ,
pubmed-author:SezakiHitomiH,
pubmed-author:SomeyaTakashiT,
pubmed-author:SuzukiFumitakaF,
pubmed-author:SuzukiYoshiyukiY,
pubmed-author:WatahikiSachiyoS
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pubmed:copyrightInfo |
Copyright (c) 2005 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
372-80
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pubmed:dateRevised |
2011-3-9
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pubmed:meshHeading |
pubmed-meshheading:16024941-Adult,
pubmed-meshheading:16024941-Aged,
pubmed-meshheading:16024941-Amino Acid Sequence,
pubmed-meshheading:16024941-Amino Acid Substitution,
pubmed-meshheading:16024941-Antiviral Agents,
pubmed-meshheading:16024941-Drug Resistance, Viral,
pubmed-meshheading:16024941-Drug Therapy, Combination,
pubmed-meshheading:16024941-Female,
pubmed-meshheading:16024941-Hepacivirus,
pubmed-meshheading:16024941-Hepatitis C,
pubmed-meshheading:16024941-Humans,
pubmed-meshheading:16024941-Interferons,
pubmed-meshheading:16024941-Japan,
pubmed-meshheading:16024941-Male,
pubmed-meshheading:16024941-Middle Aged,
pubmed-meshheading:16024941-Molecular Sequence Data,
pubmed-meshheading:16024941-Multivariate Analysis,
pubmed-meshheading:16024941-RNA, Viral,
pubmed-meshheading:16024941-Ribavirin,
pubmed-meshheading:16024941-Serum Albumin,
pubmed-meshheading:16024941-Viral Core Proteins,
pubmed-meshheading:16024941-Viral Load,
pubmed-meshheading:16024941-Viral Nonstructural Proteins
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pubmed:year |
2005
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pubmed:articleTitle |
Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy.
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pubmed:affiliation |
Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan. akuta-gi@umin.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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