rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2005-10-3
|
pubmed:abstractText |
A promoter-based length polymorphism (5-HTTLPR) of the human serotonin gene (SLC6A4) has exhibited inconsistent association with emotionality phenotypes, such as major depression (MD) and the personality trait neuroticism (N). Several explanations have been posited to account for this discrepancy, including underpowered experimental design and variation in gender ratio, age, and ethnicity.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0006-3223
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
451-6
|
pubmed:dateRevised |
2007-8-13
|
pubmed:meshHeading |
pubmed-meshheading:16023085-Depression,
pubmed-meshheading:16023085-Female,
pubmed-meshheading:16023085-Genotype,
pubmed-meshheading:16023085-Humans,
pubmed-meshheading:16023085-Male,
pubmed-meshheading:16023085-Neurotoxicity Syndromes,
pubmed-meshheading:16023085-Personality,
pubmed-meshheading:16023085-Personality Inventory,
pubmed-meshheading:16023085-Polymorphism, Genetic,
pubmed-meshheading:16023085-Psychiatric Status Rating Scales,
pubmed-meshheading:16023085-Serotonin Plasma Membrane Transport Proteins
|
pubmed:year |
2005
|
pubmed:articleTitle |
The serotonin transporter length polymorphism, neuroticism, and depression: a comprehensive assessment of association.
|
pubmed:affiliation |
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. saffron.willis-owen@well.ox.ac.uk
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|