Linked Life Data

16022631

Source:http://linkedlifedata.com/resource/pubmed/id/16022631

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-7-18
pubmed:abstractText
The ability of tumors to invade, colonize, and destroy distant organs was first recognized by Jean-Claude Recamier in 1829. He termed this phenomenon metastasis. Since it was first described, metastasis has been shown to be a complex multistep process. One important step is cell migrationa critical component of both cancer-cell invasion at the primary site (allowing cells to gain access to the vasculature) and for cells to penetrate the host tissue at distant sites. The aim of this review is to examine the fundamental role of migration in cancer progression and to discuss the role of the Rho family of small G proteins and their effectors in this process.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1045-4403
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-14
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Rho proteins in cell migration and metastasis.
pubmed:affiliation
Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural