Osteopontin (OPN) is a secreted integrin-binding glycophosphoprotein that may have a role in head and neck squamous cell carcinoma (SCC). To evaluate the clinical significance of OPN in esophageal squamous cell carcinoma (ESCC), we compared plasma OPN levels with those of common tumor markers.
Department of Surgery and Surgical Basic Science, Graduate School of Medicine, Kyoto University, 54 Kawaracho, Shogoin Sakyo-ku, Kyoto, Japan. shimada@kuhp.kyoto-u.ac.jp