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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1992-7-15
pubmed:abstractText
The immunogenic efficacy of the first batch of indigenous purified chick embryo cell culture grown (PCEC) rabies virus vaccine has been measured in ten subjects. All of them were immunologically naive to rabies virus, and were given 5 doses of the vaccine in the post-exposure regime of injections on days 0, 3, 7, 14 and 30. On day 7, four subjects had developed very low levels of rabies virus neutralizing antibody, as detected and measured in the suckling mouse neutralization test. On day 14, all subjects had protective levels of antibody, which were maintained or enhanced by day 30. With the limited data presented here, the immunogenic efficacy of this batch of vaccine appeared similar to that of a batch of imported PCEC vaccine investigated earlier.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0971-5916
pubmed:author
pubmed:issnType
Print
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Immune response to purified chick embryo cell culture rabies vaccine manufactured in India.
pubmed:affiliation
Department of Virology & Immunology, Christian Medical College & Hospital, Vellore.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't