Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1992-7-16
|
pubmed:abstractText |
In a sample of 160 Dutch twin pairs and their parents, we found that mothers of dizygotic twins had frequencies of the S and Z alleles at the protease inhibitor (Pi) locus that were 3 times higher than a control sample. Mothers of identical twins also had a higher frequency of S than controls. The S allele may thus both increase ovulation rate and enhance the success of multiple pregnancies. There was also an increased frequency of the S allele in fathers of dizygotic twins; however, this may be a secondary effect of assortative mating for family size (indicating by the number of siblings of the parents), for which a correlation of 0.2 was observed. Parents of dizygotic twins came from larger families than parents of monozygotic twins, but no effect of Pi type on family size was seen.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0340-6717
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
89
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
329-32
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:1601424-Alleles,
pubmed-meshheading:1601424-Family Characteristics,
pubmed-meshheading:1601424-Female,
pubmed-meshheading:1601424-Fertility,
pubmed-meshheading:1601424-Gene Frequency,
pubmed-meshheading:1601424-Humans,
pubmed-meshheading:1601424-Male,
pubmed-meshheading:1601424-Middle Aged,
pubmed-meshheading:1601424-Phenotype,
pubmed-meshheading:1601424-Polymorphism, Genetic,
pubmed-meshheading:1601424-Pregnancy,
pubmed-meshheading:1601424-Pregnancy, Multiple,
pubmed-meshheading:1601424-Twins,
pubmed-meshheading:1601424-Twins, Dizygotic,
pubmed-meshheading:1601424-Twins, Monozygotic,
pubmed-meshheading:1601424-alpha 1-Antitrypsin
|
pubmed:year |
1992
|
pubmed:articleTitle |
Protease inhibitor (Pi) locus, fertility and twinning.
|
pubmed:affiliation |
Department of Psychonomics, Free University, Amsterdam, The Netherlands.
|
pubmed:publicationType |
Journal Article
|