Linked Life Data

16011328

Source:http://linkedlifedata.com/resource/pubmed/id/16011328

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
28
pubmed:dateCreated
2005-7-13
pubmed:abstractText
We report the preparation of recyclable heterogeneous catalysts, copper-exchanged fluorapatite, and copper-exchanged tert-butoxyapatite by incorporating basic species F-/tBuO- in apatite in situ by coprecipitation and subsequent exchange with Cu(II). These basic copper catalysts catalyzed N-arylation of imidazoles and other heterocycles with chloroarenes and electron-poor fluoroarenes in good to excellent yields. Synthesis and characterization of some of the intermediates of the catalytic cycle gave some insight into the mechanism of the very important organic transformation. The necessity of basic sites for the activation of C-Cl and C-F bonds in the N-arylation of heterocycles with haloarenes is well-established.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Jul
pubmed:issn
0002-7863
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
127
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9948-9
pubmed:dateRevised
2008-1-17
pubmed:year
2005
pubmed:articleTitle
Design and evolution of copper apatite catalysts for N-arylation of heterocycles with chloro- and fluoroarenes.
pubmed:affiliation
Inorganic Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India. bmchoudary@yahoo.com
pubmed:publicationType
Journal Article