Source:http://linkedlifedata.com/resource/pubmed/id/16006970
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-7-11
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pubmed:abstractText |
: Interleukin-6 (IL-6) has an important role during prostate cancer progression and IL-6 levels in the serum of patients with hormone refractory and metastatic prostate cancer are significantly increased compared with those in patients with hormone sensitive and localized prostate cancer. The G>C polymorphism at position -174 in the promoter of the IL-6 gene has been associated with differences in IL-6 transcription in vitro and IL-6 protein levels in vivo. We determined the association of IL-6 polymorphism with prostate cancer progression.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-5347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
174
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
753-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16006970-Adipose Tissue,
pubmed-meshheading:16006970-Blood Vessels,
pubmed-meshheading:16006970-Genetic Predisposition to Disease,
pubmed-meshheading:16006970-Humans,
pubmed-meshheading:16006970-Interleukin-6,
pubmed-meshheading:16006970-Male,
pubmed-meshheading:16006970-Neoplasm Invasiveness,
pubmed-meshheading:16006970-Neoplasm Recurrence, Local,
pubmed-meshheading:16006970-Polymorphism, Genetic,
pubmed-meshheading:16006970-Prostatic Neoplasms,
pubmed-meshheading:16006970-Retrospective Studies,
pubmed-meshheading:16006970-Seminal Vesicles
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pubmed:year |
2005
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pubmed:articleTitle |
Interleukin-6 polymorphism is associated with more aggressive prostate cancer.
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pubmed:affiliation |
Department of Pathology, Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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