Linked Life Data

16004482

Source:http://linkedlifedata.com/resource/pubmed/id/16004482

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-7-11
pubmed:abstractText
We report on the self-assembly mechanism and dynamics in a series of poly(gamma-benzyl-l-glutamate)-b-poly(glycine) (PBLG-b-PGly) diblock copolymers within the composition range 0.67 < or = f(PBLG) < or = 0.97 and the temperature (T) range 303 < T < 433 K. Small- and wide-angle X-ray scattering, (13)C NMR, and differential scanning calorimetry are used for the structure investigation coupled with dielectric spectroscopy for both the peptide secondary structure and the associated dynamics. These techniques provide not only the nanophase morphology but also the type and persistence of peptide secondary structures. The thermodynamic confinement of the blocks within the nanodomains and the disparity in their packing efficiency results in multiple chain folding of the PGly secondary structure that effectively stabilize a lamellar morphology for high f(PBLG). Nanoscale confinement proves to be important in controlling the persistence length of secondary peptide motifs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1525-7797
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2352-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Nanodomain-induced chain folding in poly(gamma-benzyl-L-glutamate)-b-polyglycine diblock copolymers.
pubmed:affiliation
Department of Physics, University of Ioannina P.O. Box 1186, 451 10 Ioannina, Greece.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't