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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-7-8
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pubmed:abstractText |
A recent in vitro study has shown that risperidone is a substrate of P-glycoprotein. The aim of this study was to confirm the effects of verapamil, a P-glycoprotein inhibitor, on the pharmacokinetics of risperidone.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0009-9236
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-51
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16003291-Administration, Oral,
pubmed-meshheading:16003291-Adult,
pubmed-meshheading:16003291-Area Under Curve,
pubmed-meshheading:16003291-Biological Availability,
pubmed-meshheading:16003291-Chromatography, Liquid,
pubmed-meshheading:16003291-Cross-Over Studies,
pubmed-meshheading:16003291-Cytochrome P-450 CYP2D6,
pubmed-meshheading:16003291-Drug Administration Schedule,
pubmed-meshheading:16003291-Drug Synergism,
pubmed-meshheading:16003291-Genotype,
pubmed-meshheading:16003291-Half-Life,
pubmed-meshheading:16003291-Humans,
pubmed-meshheading:16003291-Immunoenzyme Techniques,
pubmed-meshheading:16003291-Isoxazoles,
pubmed-meshheading:16003291-Japan,
pubmed-meshheading:16003291-Male,
pubmed-meshheading:16003291-P-Glycoprotein,
pubmed-meshheading:16003291-Patient Selection,
pubmed-meshheading:16003291-Prolactin,
pubmed-meshheading:16003291-Pyrimidines,
pubmed-meshheading:16003291-Risperidone,
pubmed-meshheading:16003291-Statistics as Topic,
pubmed-meshheading:16003291-Verapamil
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pubmed:year |
2005
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pubmed:articleTitle |
Effect of verapamil on pharmacokinetics and pharmacodynamics of risperidone: in vivo evidence of involvement of P-glycoprotein in risperidone disposition.
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pubmed:affiliation |
Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki 036-8562, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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