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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-7-10
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pubmed:abstractText |
The levels of atherogenic lipid fractions are higher in children with a family history of ischemic cardiovascular disease (CD). This study was designed to examine this relationship in neonates. A total of 1276 newborns were investigated; 400 cord blood samples were collected for measurement of triglycerides (TG), total cholesterol (TC), LDL cholesterol (LDL-C) and HDL cholesterol (HDL-C); on day 4, 1200 capillary samples were taken for TC and TG measurements. Male newborns with a positive history of CD had higher concentrations of cord blood TC (P less than 0.04) and LDL-C (P less than 0.02). On day 4 this difference in TC was no longer detectable (LDL-C not determined). A coronary heart disease (CHD) risk factor family history is sensitive (0.87) in predicting high cord blood concentrations of LDL-C, the specificity being 0.46 and the positive predicting value 0.08.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0803-5253
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1600298-Cardiovascular Diseases,
pubmed-meshheading:1600298-Cholesterol,
pubmed-meshheading:1600298-Cholesterol, HDL,
pubmed-meshheading:1600298-Cholesterol, LDL,
pubmed-meshheading:1600298-Female,
pubmed-meshheading:1600298-Humans,
pubmed-meshheading:1600298-Infant, Newborn,
pubmed-meshheading:1600298-Lipids,
pubmed-meshheading:1600298-Male,
pubmed-meshheading:1600298-Risk Factors,
pubmed-meshheading:1600298-Sex Factors,
pubmed-meshheading:1600298-Triglycerides
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pubmed:year |
1992
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pubmed:articleTitle |
Familial history of cardiovascular disease and blood lipid pattern in newborn infants.
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pubmed:affiliation |
Department of Pediatrics V, University of Milan, Italy.
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pubmed:publicationType |
Journal Article
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