Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Suppl
pubmed:dateCreated
2005-7-8
pubmed:abstractText
Surgical therapy is currently the only proven way to achieve significant long-term weight loss, improve obesity-related comorbidities, reduce the risk of premature death, and improve quality of life in a large proportion of treated individuals. Roux-en-Y gastric bypass, the most widely performed procedure in the United States, is known to achieve permanent (>14 y of follow-up) and significant (>50% of excess body weight) weight loss in >90% of patients who undergo the operation. Gastric bypass procedures induce physiologic and neuroendocrine changes that appear to affect the weight regulatory centers in the brain. Researchers have begun to explore the molecular pathways responsible for these outcomes. Identifying the differences between surgical and nonsurgical treatments will eventually lead to new therapeutic options.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9165
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
248S-252S
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Solutions in weight control: lessons from gastric surgery.
pubmed:affiliation
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. gblackbu@bidmc.harvard.edu
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't