Source:http://linkedlifedata.com/resource/pubmed/id/15996263
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2005-7-5
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pubmed:abstractText |
T-cell post-transplant lymphoproliferative disorder (PTLD) is a rare life threatening complication of organ transplantation. It is usually resistant to treatment with reduction in immunosuppression or chemotherapy and carries a poor prognosis. We report on a combined kidney and pancreas transplant patient with Epstein-Barr virus (EBV) positive T-cell PTLD that had recurred after chemotherapy and reduction in immunosuppression. The patient was successfully treated with bexarotene, a novel synthetic retinoid analog, achieving a complete clinical response. Bexarotene may be a promising treatment for T-cell PTLD.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1600-6135
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2070-3
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pubmed:dateRevised |
2007-2-14
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pubmed:meshHeading |
pubmed-meshheading:15996263-Anticarcinogenic Agents,
pubmed-meshheading:15996263-Epstein-Barr Virus Infections,
pubmed-meshheading:15996263-Herpesvirus 4, Human,
pubmed-meshheading:15996263-Humans,
pubmed-meshheading:15996263-Immunosuppression,
pubmed-meshheading:15996263-Kidney Transplantation,
pubmed-meshheading:15996263-Lymphoma, T-Cell, Peripheral,
pubmed-meshheading:15996263-Male,
pubmed-meshheading:15996263-Middle Aged,
pubmed-meshheading:15996263-Postoperative Complications,
pubmed-meshheading:15996263-Tetrahydronaphthalenes,
pubmed-meshheading:15996263-Viral Load
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pubmed:year |
2005
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pubmed:articleTitle |
Successful treatment of T-cell post-transplant lymphoproliferative disorder with the retinoid analog bexarotene.
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pubmed:affiliation |
Hematologic Malignancies Program, University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, USA. detsai@mail.med.upenn.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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