Source:http://linkedlifedata.com/resource/pubmed/id/15995970
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2005-7-4
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pubmed:abstractText |
Activation of the indoleamine 2,3-dioxygenase (IDO) enzyme and the resulting decrease in plasma tryptophan (TRP) levels appears to be a crucial link in the relationship between cytokines and depression. We aimed to develop an experimental model of chronic IDO activation based on bacille Calmette-Guérin (BCG) infection that elicits a robust increase in levels of interferon (IFN)- gamma, a key cytokine in the activation of IDO.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
192
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
537-44
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15995970-Animals,
pubmed-meshheading:15995970-BCG Vaccine,
pubmed-meshheading:15995970-Brain,
pubmed-meshheading:15995970-Enzyme Activation,
pubmed-meshheading:15995970-Indoleamine-Pyrrole 2,3,-Dioxygenase,
pubmed-meshheading:15995970-Interferon-gamma,
pubmed-meshheading:15995970-Liver,
pubmed-meshheading:15995970-Male,
pubmed-meshheading:15995970-Mice,
pubmed-meshheading:15995970-Tryptophan Oxygenase
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pubmed:year |
2005
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pubmed:articleTitle |
Bacille Calmette-Guérin inoculation induces chronic activation of peripheral and brain indoleamine 2,3-dioxygenase in mice.
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pubmed:affiliation |
Laboratory of Neurobiologie Integrative, Formation de Recherche en Evolution 2723 Centre National de la Recherche Scientifique-Unite Mixte de Recherche 1244 Institut National de Recherche Agronomique, Institut Francois Magendie, Bordeaux, France.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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