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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2005-7-4
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pubmed:abstractText |
Gene expression profiling has provided many insights into tumor progression but translation to clinical practice has been limited. We have previously identified a list of potential markers by the differences of expression profiling of seven matched head and neck cancer (HNSCC) tumors with autologous normal oral mucosa (NOM). Alpha B-crystallin (CRYAB) was in the top 5% of genes identified with statistically significant differences in expression between tumor and NOM at the mRNA level. The objective was to confirm this in routine paraffin sections at the protein level.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0023-852X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1239-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15995513-Adult,
pubmed-meshheading:15995513-Aged,
pubmed-meshheading:15995513-Aged, 80 and over,
pubmed-meshheading:15995513-Biological Markers,
pubmed-meshheading:15995513-Female,
pubmed-meshheading:15995513-Follow-Up Studies,
pubmed-meshheading:15995513-Humans,
pubmed-meshheading:15995513-Immunohistochemistry,
pubmed-meshheading:15995513-Male,
pubmed-meshheading:15995513-Middle Aged,
pubmed-meshheading:15995513-Mouth Mucosa,
pubmed-meshheading:15995513-Neoplasm Staging,
pubmed-meshheading:15995513-Oropharyngeal Neoplasms,
pubmed-meshheading:15995513-Prognosis,
pubmed-meshheading:15995513-RNA, Messenger,
pubmed-meshheading:15995513-Survival Rate,
pubmed-meshheading:15995513-Time Factors,
pubmed-meshheading:15995513-Tongue Neoplasms,
pubmed-meshheading:15995513-alpha-Crystallin B Chain
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pubmed:year |
2005
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pubmed:articleTitle |
Alpha B-crystallin, a new independent marker for poor prognosis in head and neck cancer.
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pubmed:affiliation |
Melanoma Genomics Group, Queensland Institute of Medical Research, Herston, Brisbane, Queensland, Australia. davidC@qimr.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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