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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-8-22
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pubmed:abstractText |
Transforming growth factor beta (TGF-beta) is a multifunctional cytokine that strongly inhibits epithelial cell growth. Disabling of TGF-beta signaling is thought to be involved in development of a variety of tumors in which abnormal expression or function of TGF-beta receptor plays critical roles. In the present study, we examined aberrant expression and mutation of the gene TGF-beta receptor type II (TbetaRII) in endometrial cancers of endometrioid subtype.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0090-8258
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
98
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
427-33
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15993480-Acetylation,
pubmed-meshheading:15993480-Adult,
pubmed-meshheading:15993480-Aged,
pubmed-meshheading:15993480-Base Pair Mismatch,
pubmed-meshheading:15993480-DNA Methylation,
pubmed-meshheading:15993480-DNA Mutational Analysis,
pubmed-meshheading:15993480-DNA Repair,
pubmed-meshheading:15993480-Endometrial Neoplasms,
pubmed-meshheading:15993480-Female,
pubmed-meshheading:15993480-Frameshift Mutation,
pubmed-meshheading:15993480-Histones,
pubmed-meshheading:15993480-Humans,
pubmed-meshheading:15993480-Middle Aged,
pubmed-meshheading:15993480-Polymerase Chain Reaction,
pubmed-meshheading:15993480-Promoter Regions, Genetic,
pubmed-meshheading:15993480-Protein-Serine-Threonine Kinases,
pubmed-meshheading:15993480-RNA, Messenger,
pubmed-meshheading:15993480-Receptors, Transforming Growth Factor beta,
pubmed-meshheading:15993480-Signal Transduction
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pubmed:year |
2005
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pubmed:articleTitle |
Aberrant expression and mutations of TGF-beta receptor type II gene in endometrial cancer.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8641, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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