|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
18
|
|
pubmed:dateCreated |
2005-8-15
|
|
pubmed:abstractText |
The structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues have been investigated as TRPV1 receptor antagonists. A docking model of potent antagonist 2 with the sensor region of TRPV1 is proposed.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0960-894X
|
|
pubmed:author |
pubmed-author:BlumbergPeter MPM,
pubmed-author:ChoSookhyunS,
pubmed-author:ChoiHyun-KyungHK,
pubmed-author:ChoiYeon-SilYS,
pubmed-author:HaHee-JinHJ,
pubmed-author:HwangJaeminJ,
pubmed-author:JinMi-KyoungMK,
pubmed-author:KangSang-UkSU,
pubmed-author:KimSu YeonSY,
pubmed-author:KimSung-EunSE,
pubmed-author:KimYoung-HoYH,
pubmed-author:LazarJozsefJ,
pubmed-author:LeeJeewooJ,
pubmed-author:LeeJiyounJ,
pubmed-author:LeeYong-SilYS,
pubmed-author:LundbergDaniel JDJ,
pubmed-author:MorganMatthew AMA,
pubmed-author:PavlyukovetsVladimir AVA,
pubmed-author:PearceLarry VLV,
pubmed-author:ShinMyoungyoupM,
pubmed-author:SuhYoung-GerYG,
pubmed-author:SzaboTamasT,
pubmed-author:TothAttilaA,
pubmed-author:TranRichardR,
pubmed-author:WangYunY,
pubmed-author:WelterJacqueline DJD
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
15
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
4143-50
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15993063-Animals,
pubmed-meshheading:15993063-CHO Cells,
pubmed-meshheading:15993063-Cricetinae,
pubmed-meshheading:15993063-Ligands,
pubmed-meshheading:15993063-Models, Molecular,
pubmed-meshheading:15993063-Protein Structure, Tertiary,
pubmed-meshheading:15993063-Structure-Activity Relationship,
pubmed-meshheading:15993063-Sulfonamides,
pubmed-meshheading:15993063-TRPV Cation Channels,
pubmed-meshheading:15993063-Thiocarbamates,
pubmed-meshheading:15993063-Thiourea
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.
|
|
pubmed:affiliation |
Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea. jeewoo@snu.ac.kr
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
