rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2005-6-30
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pubmed:abstractText |
Gamma-aminobutyric acid (GABA)-A/benzodiazepine receptors (BZRs) play an important inhibitory role in epileptogenesis. [123I]Iomazenil (123I-IMZ) is a specific ligand for central-type (or neuronal-type) BNRs and is available for single-photon emission computed tomography (SPECT) in brain disorders. We demonstrated alterations of central-type BZRs in human focal epilepsies and their experimental models.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0013-9580
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
46 Suppl 5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
184-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15987275-Adult,
pubmed-meshheading:15987275-Amygdala,
pubmed-meshheading:15987275-Animals,
pubmed-meshheading:15987275-Autoradiography,
pubmed-meshheading:15987275-Cerebral Cortex,
pubmed-meshheading:15987275-Dentate Gyrus,
pubmed-meshheading:15987275-Disease Models, Animal,
pubmed-meshheading:15987275-Epilepsies, Partial,
pubmed-meshheading:15987275-Epilepsy, Temporal Lobe,
pubmed-meshheading:15987275-Female,
pubmed-meshheading:15987275-Flumazenil,
pubmed-meshheading:15987275-Hippocampus,
pubmed-meshheading:15987275-Humans,
pubmed-meshheading:15987275-Iodine Radioisotopes,
pubmed-meshheading:15987275-Kainic Acid,
pubmed-meshheading:15987275-Kindling, Neurologic,
pubmed-meshheading:15987275-Magnetic Resonance Imaging,
pubmed-meshheading:15987275-Male,
pubmed-meshheading:15987275-Neocortex,
pubmed-meshheading:15987275-Rats,
pubmed-meshheading:15987275-Receptors, GABA-A,
pubmed-meshheading:15987275-Regional Blood Flow,
pubmed-meshheading:15987275-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
2005
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pubmed:articleTitle |
Central-type benzodiazepine receptors and epileptogenesis: basic mechanisms and clinical validity.
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pubmed:affiliation |
Department of Neuropsychiatry, Faculty of Medicine, Kagawa Medical University, Kagawa, Japan. neuropsy@kms.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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