15986008

Source:http://linkedlifedata.com/resource/pubmed/id/15986008

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0012634, umls-concept:C0018787, umls-concept:C0035647, umls-concept:C0242698, umls-concept:C1524062, umls-concept:C2607943, umls-concept:C2708283, umls-concept:C2926606
pubmed:issue	2
pubmed:dateCreated	2005-6-29
pubmed:abstractText	Tako-tsubo-like left ventricular dysfunction phenomenon (TTP) has primarily been described in Japan and is characterized by transient left ventricular apical ballooning in the absence of coronary artery disease, associated with chest symptoms, electrocardiographic changes and minimal cardiac enzymes release. Aim of the present review is to summarize the current knowledge about TTP. TTP has been described predominantly in females. TTP occurs also outside Japan. Clinical symptoms comprise anginal chest pain, dyspnea and syncope. TTP occurs frequently after acute emotional or physical stress. Electrocardiographic ST- elevations may be present only for several hours. Then, normalization of the ST-segment occurs, followed by negative T waves, which persist for months. Arterial hypertension in TTP is found in up to 76%, hyperlipidaemia in up to 57%, diabetes mellitus in up to 12% and smoking in up to 18% of the patients. Several pathomechanisms have been proposed: myocardial stunning due to increased catecholamine levels, coronary vasospasm, atherosclerotic plaques rupture, myocarditis, catecholamine-induced hyperkinesis of the basal left ventricular segments and genetic. Patients with TTP should be monitored like patients with myocardial infarction. Care should be taken in the application of catecholamines and nitrates. Betablockers should be given in the acute and chronic phase, and possibly indefinitely to prevent recurrences. The prognosis of TTP is assumed to be good, but in the acute phase there are deaths due to multisystem organ failure, cardiogenic shock, ventricular fibrillation and ventricular rupture. The long term prognosis of TTP patients is largely unknown.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0400725
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0026-4725
pubmed:author	pubmed-author:FinstererJJ, pubmed-author:SchneiderBB, pubmed-author:StöllbergerCC
pubmed:issnType	Print
pubmed:volume	53
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	139-45
pubmed:meshHeading	pubmed-meshheading:15986008-Humans, pubmed-meshheading:15986008-Takotsubo Cardiomyopathy, pubmed-meshheading:15986008-Ventricular Dysfunction, Left
pubmed:year	2005
pubmed:articleTitle	Tako-tsubo-like left ventricular dysfunction: clinical presentation, instrumental findings, additional cardiac and non-cardiac diseases and potential pathomechanisms.
pubmed:affiliation	Krankenanstalt Rudolfstiftung, Medizinische Abteilung, Wien, Osterreich. claudia.stoellberger@chello.at
pubmed:publicationType	Journal Article, Review