| pubmed-article:15984157 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C1135183 | lld:lifeskim |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C0013935 | lld:lifeskim |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C0018590 | lld:lifeskim |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C1332397 | lld:lifeskim |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:15984157 | lifeskim:mentions | umls-concept:C0021149 | lld:lifeskim |
| pubmed-article:15984157 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:15984157 | pubmed:dateCreated | 2005-6-29 | lld:pubmed |
| pubmed-article:15984157 | pubmed:abstractText | The objective of this study was to determine developmental pattern, total cell number, apoptosis and apoptosis-related gene expression in haploid and diploid embryos following parthenogenetic activation. In vitro-matured porcine oocytes were activated by electrical pulses and cultured in the absence or presence of cytochalasin B for 3 h. Zygotes with two polar bodies (haploid) and one polar body (diploid) were carefully selected and were further cultured in NCSU 23 medium containing 0.4% bovine serum albumin (BSA) for 7 days. The percentage of development to blastocyst stage was higher (p < 0.01) in the diploid than in the haploid parthenotes. In haploid blastocysts, average total cell number was significantly reduced (p < 0.05) and apoptosis was increased at day 7. The relative abundance of Bcl-xL and Bak mRNA in the diploid blastocysts was similar to that of in vivo-fertilized embryos. However, Bcl-xL was significantly decreased, and Bak mRNA was significantly increased (p < 0.05) in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis and decreased developmental competence of haploid parthenotes. | lld:pubmed |
| pubmed-article:15984157 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15984157 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15984157 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15984157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15984157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15984157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15984157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15984157 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15984157 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15984157 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:15984157 | pubmed:issn | 0967-1994 | lld:pubmed |
| pubmed-article:15984157 | pubmed:author | pubmed-author:KimNam-HyungN... | lld:pubmed |
| pubmed-article:15984157 | pubmed:author | pubmed-author:LeonianL HLH | lld:pubmed |
| pubmed-article:15984157 | pubmed:author | pubmed-author:CuiXiang-Shun... | lld:pubmed |
| pubmed-article:15984157 | pubmed:author | pubmed-author:JeongYu-Jeong... | lld:pubmed |
| pubmed-article:15984157 | pubmed:author | pubmed-author:KimTeoanT | lld:pubmed |
| pubmed-article:15984157 | pubmed:author | pubmed-author:KimIl HwaIH | lld:pubmed |
| pubmed-article:15984157 | pubmed:author | pubmed-author:ChungYon-BokY... | lld:pubmed |
| pubmed-article:15984157 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15984157 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:15984157 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15984157 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15984157 | pubmed:pagination | 17-21 | lld:pubmed |
| pubmed-article:15984157 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:15984157 | pubmed:meshHeading | pubmed-meshheading:15984157... | lld:pubmed |
| pubmed-article:15984157 | pubmed:meshHeading | pubmed-meshheading:15984157... | lld:pubmed |
| pubmed-article:15984157 | pubmed:meshHeading | pubmed-meshheading:15984157... | lld:pubmed |
| pubmed-article:15984157 | pubmed:meshHeading | pubmed-meshheading:15984157... | lld:pubmed |
| pubmed-article:15984157 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15984157 | pubmed:articleTitle | Haploidy influences Bak and Bcl-xL mRNA expression and increases incidence of apoptosis in porcine embryos. | lld:pubmed |
| pubmed-article:15984157 | pubmed:affiliation | Department of Animal Sciences, Research Center for Bioresource and Health, Cheongju, Chungbuk, South Korea. | lld:pubmed |
| pubmed-article:15984157 | pubmed:publicationType | Journal Article | lld:pubmed |
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| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15984157 | lld:entrezgene |
