rdf:type |
|
lifeskim:mentions |
umls-concept:C0010405,
umls-concept:C0018787,
umls-concept:C0034693,
umls-concept:C0040223,
umls-concept:C0040715,
umls-concept:C0599718,
umls-concept:C0599813,
umls-concept:C0599893,
umls-concept:C1332397,
umls-concept:C1517499,
umls-concept:C1522702
|
pubmed:issue |
1
|
pubmed:dateCreated |
2005-7-6
|
pubmed:abstractText |
Apoptosis is an important cause of early graft loss after heart transplantation. Bcl-xL was reported to protect the heart against normothermic ischemia and reperfusion injury. In this study, we determined whether overexpression of Bcl-xL could inhibit tissue injury resulting from prolonged cold preservation followed by warm reperfusion of heart transplants.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1524-4539
|
pubmed:author |
pubmed-author:HamadaHirofumiH,
pubmed-author:HiraiSachieS,
pubmed-author:HuangJianhuaJ,
pubmed-author:IshiiKeijiK,
pubmed-author:ItoYoshinoriY,
pubmed-author:KatoKazunoriK,
pubmed-author:MasutaYukariY,
pubmed-author:MorikawaMasayukiM,
pubmed-author:NakamuraKiminoriK,
pubmed-author:TanakaToshihiroT,
pubmed-author:TomiharaKeiK,
pubmed-author:UzukaTakeshiT
|
pubmed:issnType |
Electronic
|
pubmed:day |
5
|
pubmed:volume |
112
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
76-83
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15983241-Animals,
pubmed-meshheading:15983241-Apoptosis,
pubmed-meshheading:15983241-Cryopreservation,
pubmed-meshheading:15983241-Cytosol,
pubmed-meshheading:15983241-Graft Survival,
pubmed-meshheading:15983241-Heart,
pubmed-meshheading:15983241-Heart Transplantation,
pubmed-meshheading:15983241-Male,
pubmed-meshheading:15983241-Mitochondria, Heart,
pubmed-meshheading:15983241-Myocardial Reperfusion,
pubmed-meshheading:15983241-Myocardial Reperfusion Injury,
pubmed-meshheading:15983241-Myocardium,
pubmed-meshheading:15983241-Organ Preservation,
pubmed-meshheading:15983241-Protein Transport,
pubmed-meshheading:15983241-Rats,
pubmed-meshheading:15983241-Rats, Inbred Lew,
pubmed-meshheading:15983241-Transduction, Genetic,
pubmed-meshheading:15983241-bcl-2-Associated X Protein,
pubmed-meshheading:15983241-bcl-X Protein
|
pubmed:year |
2005
|
pubmed:articleTitle |
Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rats.
|
pubmed:affiliation |
Department of Molecular Medicine, Sapporo Medical University, Sapporo, 060-8556, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|