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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-6-28
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pubmed:databankReference |
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pubmed:abstractText |
Four new HLA classical class I alleles in the three loci are described in Caucasian individuals. A*3012 was first suspected by an abnormal serologic pattern that would be explained by the single amino acid substitution at the A30-specific Ser17. B*270505 differs from B*270502 in a silent substitution at an up to now constant position in the B locus. B*3541 encodes for a new Cys at position 118 that has not been encountered in neither human nor primate alleles. Cw*0716 seems to be originated by a large-scale interallelic recombination event between Cw*0701/*0706/*0718 and Cw*020202, giving rise to a new antigen-binding cleft conformation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0001-2815
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
51-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15982258-Alleles,
pubmed-meshheading:15982258-Amino Acid Sequence,
pubmed-meshheading:15982258-Base Sequence,
pubmed-meshheading:15982258-Cysteine,
pubmed-meshheading:15982258-European Continental Ancestry Group,
pubmed-meshheading:15982258-Genes, MHC Class I,
pubmed-meshheading:15982258-HLA-A Antigens,
pubmed-meshheading:15982258-HLA-B Antigens,
pubmed-meshheading:15982258-HLA-C Antigens,
pubmed-meshheading:15982258-Heterozygote,
pubmed-meshheading:15982258-Histocompatibility Antigens Class I,
pubmed-meshheading:15982258-Histocompatibility Testing,
pubmed-meshheading:15982258-Humans,
pubmed-meshheading:15982258-Introns,
pubmed-meshheading:15982258-Molecular Sequence Data,
pubmed-meshheading:15982258-Mutation,
pubmed-meshheading:15982258-Polymorphism, Genetic,
pubmed-meshheading:15982258-Recombination, Genetic
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pubmed:year |
2005
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pubmed:articleTitle |
Four new HLA class I alleles in Cauacasoids.
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pubmed:affiliation |
Laboratory of Histocompatibility, Regional Transfusion Center, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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