Source:http://linkedlifedata.com/resource/pubmed/id/15981755
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-6-28
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pubmed:abstractText |
Patients with thrombotic thrombocytopenic purpura (TTP) are deficient in von Willebrand factor (VWF)-cleaving protease, called ADAMTS13, and are prone to develop abnormal intravascular platelet aggregation leading to focal cerebral ischaemia. We speculated that low levels of ADAMTS13 are present in premature infants. This might result in platelet aggregation with subsequent ischaemia, vessel rupture and haemorrhage, and thus contribute to intraventricular haemorrhage and periventricular leucomalacia (IVH and PVL).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0803-5253
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
205-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15981755-ADAM Proteins,
pubmed-meshheading:15981755-Birth Weight,
pubmed-meshheading:15981755-Case-Control Studies,
pubmed-meshheading:15981755-Gestational Age,
pubmed-meshheading:15981755-Humans,
pubmed-meshheading:15981755-Infant, Newborn,
pubmed-meshheading:15981755-Infant, Premature,
pubmed-meshheading:15981755-Linear Models,
pubmed-meshheading:15981755-Metalloendopeptidases,
pubmed-meshheading:15981755-Pilot Projects,
pubmed-meshheading:15981755-von Willebrand Factor
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pubmed:year |
2005
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pubmed:articleTitle |
VWF-cleaving protease (ADAMTS13) in premature infants.
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pubmed:affiliation |
Department of Paediatrics, Lund University, Lund, Sweden. lena.westas@skane.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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