Linked Life Data

15980781

Source:http://linkedlifedata.com/resource/pubmed/id/15980781

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2005-6-27
pubmed:abstractText
While cigarette smoking continues to increase among women, the influence of maternal smoking during pregnancy on the prevalence of malformations has been widely investigated over the past 30 years. Although many women discontinue smoking during pregnancy, the fetus is still often exposed during first weeks of gestation, including embryological development, raising questions about the teratogenic effect of smoking. We review the literature on this topic highlighting methodological issues. The overall prevalence of malformations does not seem to be increased among offspring of women who smoked during pregnancy. A mild but significant association was found between several specific malformations (oral cleft, gastroschisis and craniosynostosis) and maternal smoking. Though the odds ratios were very low for these associations, the change in absolute number, especially for facial clefts, is important due to high prevalence of smoking during pregnancy. These findings should be taken into account in preconceptional counselling.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0368-2315
pubmed:author
pubmed:issnType
Print
pubmed:volume
34 Spec No 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3S124-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
[Maternal cigarette smoking during pregnancy and malformations].
pubmed:affiliation
Centre de Renseignements sur les Agents Tératogènes, Hôpital Armand-Trousseau, 26, avenue du Docteur-Netter, 75012 Paris.
pubmed:publicationType
Journal Article, English Abstract, Review