Linked Life Data

15980586

Source:http://linkedlifedata.com/resource/pubmed/id/15980586

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Web Server issue
pubmed:dateCreated
2005-6-27
pubmed:abstractText
ProTarget is a Web-based tool for the automatic prediction of fold novelty. It offers the structural genomics community a method for target selection by providing an online analysis of any new or pre-existing sequence for its relationship to any previously solved three-dimensional structure. ProTarget takes as input an amino acid sequence. Regions of this sequence that exhibit high similarity to an existing PDB (Protein Data Bank) sequence are removed, leaving one or more subsequences. Each of these subsequences is then analyzed against a clustering of the protein space to determine the likelihood of its representing a new structural superfamily. This likelihood is derived from the distance in the clustering between the (sub)sequence and sequences that have known structures. The output of ProTarget is a graphical visualization of the protein of interest together with the likelihood that a protein sequence represents a novel structural superfamily. ProTarget is updated regularly and currently covers over 160 000 protein sequences from the SwissProt and PDB databases. ProTarget is available at http://www.protarget.cs.huji.ac.il.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-11373627, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-11752311, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-12127459, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-12169526, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-12520059, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-12880206, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-15539447, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-15596019, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-15608180, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-9254694, http://linkedlifedata.com/resource/pubmed/commentcorrection/15980586-9846869
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1362-4962
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
W81-4
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
ProTarget: automatic prediction of protein structure novelty.
pubmed:affiliation
School of Computer Science and Engineering, Institute of Life Sciences, Hebrew University of Jerusalem, 91904 Israel.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural