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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-6-27
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pubmed:abstractText |
In aging men serum levels of testosterone and insulin-like growth factor-1 (IGF-1) decline, potential factors in the reduced muscle strength, abdominal obesity, sexual dysfunction and impaired general well being of aging. The partial oestrogen agonist and antagonist raloxifene increase serum testosterone levels in aging men, but the effect of raloxifene on serum IGF-1 levels in men is unknown. In this study the effects of raloxifene on IGF-1 levels and the associated increase in serum testosterone were compared to the effects of oral testosterone supplementation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0378-5122
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
286-93
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15978972-Administration, Oral,
pubmed-meshheading:15978972-Adolescent,
pubmed-meshheading:15978972-Adult,
pubmed-meshheading:15978972-Aged,
pubmed-meshheading:15978972-Aging,
pubmed-meshheading:15978972-Double-Blind Method,
pubmed-meshheading:15978972-Estrogen Antagonists,
pubmed-meshheading:15978972-Female,
pubmed-meshheading:15978972-Humans,
pubmed-meshheading:15978972-Insulin-Like Growth Factor Binding Protein 3,
pubmed-meshheading:15978972-Insulin-Like Growth Factor I,
pubmed-meshheading:15978972-Male,
pubmed-meshheading:15978972-Middle Aged,
pubmed-meshheading:15978972-Multivariate Analysis,
pubmed-meshheading:15978972-Raloxifene,
pubmed-meshheading:15978972-Testosterone,
pubmed-meshheading:15978972-Transsexualism
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pubmed:year |
2005
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pubmed:articleTitle |
Comparison of effects of the rise in serum testosterone by raloxifene and oral testosterone on serum insulin-like growth factor-1 and insulin-like growth factor binding protein-3.
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pubmed:affiliation |
Department of Endocrinology, VU University Medical Centre, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. e.duscheck@zonnet.nl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial
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