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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1992-7-9
|
| pubmed:abstractText |
To determine if recent trends in evaluation and therapy have contributed to the successful surgical management of carotid body paragangliomas, we reviewed our experience over the past decade. Nineteen carotid body paragangliomas were identified in 17 patients. Eleven patients underwent complete, preoperative embolization of their afferent arteries with one complication. Calculated carotid body paragangliomas surface areas did not differ between the embolized 64.6 +/- 43.3 cm2 and nonembolized 63.0 +/- 57.9 cm2 lesions. Intraoperative blood loss was lower (p = 0.02) in the patients treated with embolization (372 +/- 213 ml) compared with their cohorts (609 +/- 564 ml). However, the operative times were equivalent 4.1 hours versus 4.5 hours in both groups. Intraoperative electroencephalographic (EEG) monitoring was used in 10 patients; in one patient the EEG indicated intraoperative thrombosis of the carotid artery, which was successfully treated by thrombectomy without complications. Two patients required carotid bifurcation resection and vascular reconstruction to remove the entire tumor; a late stroke manifested by contralateral hand weakness developed in one of these patients. The incidence of cranial nerve injury was low at 16%, with one transient ramus mandibularis paresis and two instances of vocal cord dysfunction. Two additional patients had a postoperative Horner's syndrome. We conclude that by diminishing intraoperative blood loss through complete and careful preoperative embolization and use of intraoperative EEG monitoring along with careful surgical technique, the complications associated with this challenging operation are facilitated and diminished.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0741-5214
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1038-44; discussion 1044-5
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:1597886-Adult,
pubmed-meshheading:1597886-Aged,
pubmed-meshheading:1597886-Analysis of Variance,
pubmed-meshheading:1597886-Blood Loss, Surgical,
pubmed-meshheading:1597886-Carotid Body Tumor,
pubmed-meshheading:1597886-Electroencephalography,
pubmed-meshheading:1597886-Embolization, Therapeutic,
pubmed-meshheading:1597886-Female,
pubmed-meshheading:1597886-Humans,
pubmed-meshheading:1597886-Intraoperative Care,
pubmed-meshheading:1597886-Linear Models,
pubmed-meshheading:1597886-Male,
pubmed-meshheading:1597886-Middle Aged,
pubmed-meshheading:1597886-Postoperative Complications
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
The current surgical management of carotid body paragangliomas.
|
| pubmed:affiliation |
Division of Vascular Surgery, Massachusetts General Hospital, Boston 02114.
|
| pubmed:publicationType |
Journal Article
|