Source:http://linkedlifedata.com/resource/pubmed/id/15978669
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-10-24
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pubmed:abstractText |
A laser-diode forms the basis of a displacement sensitive homodyne interferometer suitable for measurements from poorly reflective surfaces. The compact and cost-effective interferometer utilizes the self-mixing effect when laser light reflected from a moving target re-enters the laser cavity and causes phase dependent changes of the lasing intensity. A piezo positioner was used to displace the interferometer with known frequency and amplitude as a basis for real-time calibration of the interferometer's sensitivity. The signal-processing algorithm is described that allows measurements in presence of high amplitude noise leading to variation of the interferometer's operating point. Measurements of sound-induced basilar membrane displacements were made in the intact cochleae of rodents by focusing the laser beam of the interferometer through the transparent round window membrane. The interferometer provides a viable means for making subnanometre mechanical measurements from structures in the inner ears of small mammals, where opening of the cochlea is not practicable.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0165-0270
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
122-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15978669-Algorithms,
pubmed-meshheading:15978669-Animals,
pubmed-meshheading:15978669-Basilar Membrane,
pubmed-meshheading:15978669-Ear, Middle,
pubmed-meshheading:15978669-Guinea Pigs,
pubmed-meshheading:15978669-Hearing,
pubmed-meshheading:15978669-Interferometry,
pubmed-meshheading:15978669-Lasers,
pubmed-meshheading:15978669-Organ of Corti,
pubmed-meshheading:15978669-Round Window, Ear,
pubmed-meshheading:15978669-Signal Processing, Computer-Assisted,
pubmed-meshheading:15978669-Vibration
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pubmed:year |
2005
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pubmed:articleTitle |
A self-mixing laser-diode interferometer for measuring basilar membrane vibrations without opening the cochlea.
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pubmed:affiliation |
School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK. a.lukashkin@sussex.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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