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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
2005-6-24
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pubmed:abstractText |
Novel 1-R-imidazole-2-nitrolic acids and 1-R-imidazole-5-nitrolic acids (R: H, Me, Bn) were synthesized from oximes by treatment with a mixture of fuming nitric acid and acetic acid. The effects of these potential nitric oxide-donating compounds were tested on ocular variables such as intraocular pressure and formation of cyclic guanosine-3,5'-monophosphate in the incubation of porcine iris-ciliary body.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-2623
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4231-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15974576-Animals,
pubmed-meshheading:15974576-Aqueous Humor,
pubmed-meshheading:15974576-Cyclic GMP,
pubmed-meshheading:15974576-Drug Design,
pubmed-meshheading:15974576-Imidazoles,
pubmed-meshheading:15974576-Iris,
pubmed-meshheading:15974576-Models, Molecular,
pubmed-meshheading:15974576-Molecular Structure,
pubmed-meshheading:15974576-Nitrates,
pubmed-meshheading:15974576-Nitrites,
pubmed-meshheading:15974576-Nitroglycerin,
pubmed-meshheading:15974576-Swine
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pubmed:year |
2005
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pubmed:articleTitle |
Synthesis and ocular effects of imidazole nitrolic acids.
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pubmed:affiliation |
Department of Chemistry, University of Joensuu, Joensuu, Finland. Larisa.Oresmaa@joensuu.fi
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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