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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2005-6-23
pubmed:abstractText
In saccade experiments, each trial (e.g. prosaccade/antisaccade) is by definition followed by a saccade, which returns the gaze back to the center (retrosaccade). This event can complicate brain-imaging results when using a simple block-design. We used an event-related functional magnetic resonance imaging design involving prosaccades and antisaccades (testsaccades) to examine brain activation associated with retrosaccades. Testsaccades activated visual and oculomotor-related brain areas. During retrosaccades, these areas were less active than during testsaccades. In the supplementary eye fields, the insula, and striatum, the retrosaccades gave rise to negative blood oxygenation level-dependent responses. In the striatum, these negative responses were equal in size to the positive responses of the testsaccades. This could mask brain activity of testsaccades when not taken into account.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0959-4965
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1043-7
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Brain activation related to retrosaccades in saccade experiments.
pubmed:affiliation
Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, the Netherlands. M.A.H.Raemaekers@azu.nl
pubmed:publicationType
Journal Article