15970265

Source:http://linkedlifedata.com/resource/pubmed/id/15970265

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011923, umls-concept:C0037813, umls-concept:C0185125, umls-concept:C0920472
pubmed:issue	12
pubmed:dateCreated	2005-6-22
pubmed:abstractText	Imaging mass spectrometry (IMS) encompasses a variety of techniques that enable the chemical imaging of analytes, which range in size from atoms and small molecules to intact proteins, directly from biological tissues. IMS is transforming specific areas in biological research with its unique combination of chemical and spatial information. Innovations in instrumentation and imaging protocols will make this approach invaluable at many stages of the drug discovery process, including pharmacological target screening and evaluating the distribution of drug and drug metabolites in cells and tissues. The fundamentals and unique methodology of IMS are discussed, along with exciting new applications to drug discovery science.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9604391
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1359-6446
pubmed:author	pubmed-author:JurchenJohn CJC, pubmed-author:MonroeEric BEB, pubmed-author:RubakhinStanislav SSS, pubmed-author:SweedlerJonathan VJV
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	10
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	823-37
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:15970265-Drug Design, pubmed-meshheading:15970265-Mass Spectrometry
pubmed:year	2005
pubmed:articleTitle	Imaging mass spectrometry: fundamentals and applications to drug discovery.
pubmed:affiliation	University of Illinois, Urbana, IL 61801, USA.
pubmed:publicationType	Journal Article, Review