Source:http://linkedlifedata.com/resource/pubmed/id/15969689
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2005-6-22
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pubmed:abstractText |
Allergic reactions occur through the exacerbated induction of a Th2 cell type expression profile and can be prevented by agents favoring a Th1 profile. Bacillus Calmette-Guérin (BCG) is able to induce high IFN-gamma levels and has been shown to decrease experimentally induced allergy. The induction of IFN-gamma is mediated by interleukin (IL)-12 known to be secreted upon mycobacterial infections and can be enhanced by IL-18 acting in synergy with IL-12.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0105-4538
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1065-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15969689-Animals,
pubmed-meshheading:15969689-BCG Vaccine,
pubmed-meshheading:15969689-Bronchi,
pubmed-meshheading:15969689-Eosinophilia,
pubmed-meshheading:15969689-Female,
pubmed-meshheading:15969689-Hypersensitivity,
pubmed-meshheading:15969689-Interleukin-18,
pubmed-meshheading:15969689-Interleukin-5,
pubmed-meshheading:15969689-Lymph Nodes,
pubmed-meshheading:15969689-Mice,
pubmed-meshheading:15969689-Mice, Inbred BALB C,
pubmed-meshheading:15969689-Pulmonary Alveoli,
pubmed-meshheading:15969689-Vaccines, Synthetic
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pubmed:year |
2005
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pubmed:articleTitle |
Recombinant Mycobacterium bovis BCG producing IL-18 reduces IL-5 production and bronchoalveolar eosinophilia induced by an allergic reaction.
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pubmed:affiliation |
Laboratoire de Microbiologie Génétique et Moléculaire, INSERM U629, Lille, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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