Linked Life Data

15969637

Source:http://linkedlifedata.com/resource/pubmed/id/15969637

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2005-6-22
pubmed:abstractText
We previously reported a long-lasting crystalline lipid pro-drug of cyclic cidofovir, hexadecyloxypropyl-cyclic-cidofovir (HDP-cCDV), to treat experimental retinitis in rabbit eyes. With HDP-cCDV there was a longer intraocular therapeutic effect than with cidofovir (CDV) and no toxicity with 100 microg/eye. It has been known that CDV and related analogues lower intraocular pressure (IOP) after local use, and it is also accepted that the guinea pig is a better model to study this toxicity before human clinical trials.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1080-7683
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
205-9
pubmed:dateRevised
2011-2-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Intraocular properties of hexadecyloxypropyl-cyclic-cidofovir in Guinea pigs.
pubmed:affiliation
Jacobs Retina Center at Shiley Eye Center, University of California, San Diego, La Jolla, CA 92093-0946, USA.
pubmed:publicationType
Journal Article