Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-6-21
pubmed:abstractText
In the adult pancreas, pre-existing beta cells, stem cells, and endocrine progenitor cells residing in the duct lining are considered important sources for beta-cell regeneration. A member of the epidermal growth factor (EGF) family, heparin binding (HB)-EGF, may promote this process. We examined whether HB-EGF gene transduction into duct cells could promote beta-cell regeneration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1536-4828
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
32-42
pubmed:dateRevised
2011-6-1
pubmed:meshHeading
pubmed-meshheading:15968245-Adenoviridae, pubmed-meshheading:15968245-Animals, pubmed-meshheading:15968245-Body Weight, pubmed-meshheading:15968245-Bromodeoxyuridine, pubmed-meshheading:15968245-Cells, Cultured, pubmed-meshheading:15968245-Diabetes Mellitus, Experimental, pubmed-meshheading:15968245-Epidermal Growth Factor, pubmed-meshheading:15968245-Gene Therapy, pubmed-meshheading:15968245-Glucose Tolerance Test, pubmed-meshheading:15968245-Homeodomain Proteins, pubmed-meshheading:15968245-Immunohistochemistry, pubmed-meshheading:15968245-Injections, pubmed-meshheading:15968245-Intercellular Signaling Peptides and Proteins, pubmed-meshheading:15968245-Islets of Langerhans, pubmed-meshheading:15968245-Male, pubmed-meshheading:15968245-Mice, pubmed-meshheading:15968245-Mice, Inbred ICR, pubmed-meshheading:15968245-Pancreatic Ducts, pubmed-meshheading:15968245-Regeneration, pubmed-meshheading:15968245-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:15968245-Trans-Activators
pubmed:year
2005
pubmed:articleTitle
Regenerative and therapeutic effects of heparin-binding epidermal growth factor-like growth factor on diabetes by gene transduction through retrograde pancreatic duct injection of adenovirus vector.
pubmed:affiliation
Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't