15967848

Source:http://linkedlifedata.com/resource/pubmed/id/15967848

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0015259, umls-concept:C0020538, umls-concept:C0037083, umls-concept:C0184511, umls-concept:C0220931, umls-concept:C1522564, umls-concept:C1710082
pubmed:issue	25
pubmed:dateCreated	2005-6-28
pubmed:abstractText	Cardiac responses to beta-adrenergic receptor stimulation are depressed with pressure overload-induced cardiac hypertrophy. We investigated whether exercise training could modify beta-adrenergic receptor responsiveness in a model of spontaneous hypertension by modifying the beta-adrenergic receptor desensitizing kinase GRK2 and the abundance and phosphorylation of some key Ca2+ cycling proteins.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/HL-33921, http://linkedlifedata.com/resource/pubmed/grant/HL-56205, http://linkedlifedata.com/resource/pubmed/grant/HL-61690
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0147763
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Adrbk1 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Agonists, http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channels, T-Type, http://linkedlifedata.com/resource/pubmed/chemical/G-Protein-Coupled Receptor Kinase 2, http://linkedlifedata.com/resource/pubmed/chemical/Isoproterenol, http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Calcium Exchanger, http://linkedlifedata.com/resource/pubmed/chemical/beta-Adrenergic Receptor Kinases
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1524-4539
pubmed:author	pubmed-author:CrabbeDeborah LDL, pubmed-author:HouserSteven RSR, pubmed-author:KochWalter JWJ, pubmed-author:KuboHajimeH, pubmed-author:LibonatiJoseph RJR, pubmed-author:MacDonnellScott MSM, pubmed-author:MoharaJunJ, pubmed-author:RegerPatricia OPO, pubmed-author:RennaBrian FBF, pubmed-author:SmithwickL AshleyLA
pubmed:issnType	Electronic
pubmed:day	28
pubmed:volume	111
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	3420-8
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:15967848-Adrenergic beta-Agonists, pubmed-meshheading:15967848-Animals, pubmed-meshheading:15967848-Blood Pressure, pubmed-meshheading:15967848-Calcium Channels, T-Type, pubmed-meshheading:15967848-Exercise Therapy, pubmed-meshheading:15967848-Female, pubmed-meshheading:15967848-G-Protein-Coupled Receptor Kinase 2, pubmed-meshheading:15967848-Heart Ventricles, pubmed-meshheading:15967848-Hypertension, pubmed-meshheading:15967848-Hypertrophy, Left Ventricular, pubmed-meshheading:15967848-Isoproterenol, pubmed-meshheading:15967848-Myocardial Contraction, pubmed-meshheading:15967848-Phosphorylation, pubmed-meshheading:15967848-Rats, pubmed-meshheading:15967848-Rats, Inbred SHR, pubmed-meshheading:15967848-Rats, Wistar, pubmed-meshheading:15967848-Sodium-Calcium Exchanger, pubmed-meshheading:15967848-beta-Adrenergic Receptor Kinases
pubmed:year	2005
pubmed:articleTitle	Improved myocardial beta-adrenergic responsiveness and signaling with exercise training in hypertension.
pubmed:affiliation	Department of Kinesiology, Temple University, Philadelphia, PA 19122, USA.
pubmed:publicationType	Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural