rdf:type |
|
lifeskim:mentions |
umls-concept:C0010346,
umls-concept:C0017262,
umls-concept:C0026473,
umls-concept:C0030705,
umls-concept:C0032105,
umls-concept:C0059290,
umls-concept:C0185117,
umls-concept:C0205254,
umls-concept:C0441889,
umls-concept:C1367477,
umls-concept:C1707520,
umls-concept:C1749467,
umls-concept:C1882417,
umls-concept:C2911684
|
pubmed:issue |
63
|
pubmed:dateCreated |
2005-6-21
|
pubmed:abstractText |
The association of the single nucleotide polymorphism in the promotor of the lipopolysaccharide receptor CD14 gene (T/C at position -159) with Crohn's disease has recently been demonstrated. This CD14 polymorphism is a potential predisposition factor responsible for inter-individual differing inflammatory reactions involving the CD14 receptor. We studied the correlation between the CD14 genotype (CC, CT, TT) and the membrane-bound CD14 monocyte expression and soluble CD14 in patients with inactive Crohn's disease.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0172-6390
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
52
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
808-11
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:15966209-Adult,
pubmed-meshheading:15966209-Antigens, CD14,
pubmed-meshheading:15966209-Crohn Disease,
pubmed-meshheading:15966209-Disease Susceptibility,
pubmed-meshheading:15966209-Female,
pubmed-meshheading:15966209-Gene Expression,
pubmed-meshheading:15966209-Genotype,
pubmed-meshheading:15966209-Humans,
pubmed-meshheading:15966209-Male,
pubmed-meshheading:15966209-Middle Aged,
pubmed-meshheading:15966209-Monocytes,
pubmed-meshheading:15966209-Polymorphism, Genetic,
pubmed-meshheading:15966209-Promoter Regions, Genetic,
pubmed-meshheading:15966209-Receptors, Immunologic,
pubmed-meshheading:15966209-Statistics as Topic
|
pubmed:articleTitle |
CD14 expression on monocytes and soluble CD14 plasma levels in correlation to the promotor polymorphism of the endotoxin receptor CD14 gene in patients with inactive Crohn's disease.
|
pubmed:affiliation |
Department of Gastroenterology, University Hospital Bergmannsheil, Bochum, Germany. thomas.griga@ruhr-uni-bochum.de
|
pubmed:publicationType |
Journal Article
|