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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
63
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pubmed:dateCreated |
2005-6-21
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pubmed:abstractText |
The local recurrence ratio following surgery alone is higher in patients with rectal cancer than in those with colon cancer. Preoperative radiotherapy reduces the rate of local recurrence and improves the chances of survival in patients with resectable advanced rectal carcinoma. Identification of predictive indicators of radiosensitivity is useful in selecting patients best suited for preoperative radiotherapy and thus helps to avoid unnecessary preoperative treatment. We investigated whether the combination of Ku, p53, p21, and p16 predicted tumor radiosensitivity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0172-6390
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
666-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15966178-Adult,
pubmed-meshheading:15966178-Aged,
pubmed-meshheading:15966178-Cell Survival,
pubmed-meshheading:15966178-Combined Modality Therapy,
pubmed-meshheading:15966178-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:15966178-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:15966178-DNA Helicases,
pubmed-meshheading:15966178-Female,
pubmed-meshheading:15966178-Follow-Up Studies,
pubmed-meshheading:15966178-Humans,
pubmed-meshheading:15966178-Immunoenzyme Techniques,
pubmed-meshheading:15966178-Male,
pubmed-meshheading:15966178-Middle Aged,
pubmed-meshheading:15966178-Neoadjuvant Therapy,
pubmed-meshheading:15966178-Neoplasm Recurrence, Local,
pubmed-meshheading:15966178-Neoplasm Staging,
pubmed-meshheading:15966178-Prognosis,
pubmed-meshheading:15966178-Rectal Neoplasms,
pubmed-meshheading:15966178-Rectum,
pubmed-meshheading:15966178-Survival Rate,
pubmed-meshheading:15966178-Treatment Outcome,
pubmed-meshheading:15966178-Tumor Markers, Biological
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pubmed:articleTitle |
Evaluating the combination of molecular prognostic factors in tumor radiosensitivity in rectal cancer.
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pubmed:affiliation |
Department of Surgical Oncology, Faculty of Medicine, University of Tokyo, Tokyo, Japan. komuro@kt.rim.or.jp
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pubmed:publicationType |
Journal Article
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