Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
2005-7-8
pubmed:abstractText
Various heterocyclic hetero-methyl ketones of the 1-naphthyloxyacetyl-Val-Asp backbone have been prepared. A study of their structure-activity relationship (SAR) related to caspase-1, -3, -6, and -8 is reported. Their efficacy in a cellular model of cell death is also discussed. Potent broad-spectrum caspase inhibitors have been identified.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3632-6
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Structure-activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads.
pubmed:affiliation
Idun Pharmaceuticals Inc., 9380 Judicial Drive, San Diego, CA 92121, USA. bullman@idun.com
pubmed:publicationType
Journal Article