Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-6-20
pubmed:abstractText
We conducted a cross-sectional study to determine the prevalence of, and risk factors for, colonization with fluoroquinolone (FQ)-resistant Escherichia coli in residents in a long-term care facility. FQ-resistant E. coli were identified from rectal swabs for 25 (51%) of 49 participants at study entry. On multivariable analyses, prior FQ use was the only independent risk factor for FQ-resistant E. coli carriage and was consistent for FQ exposures in the previous 3, 6, 9, or 12 months. Pulsed-field gel electrophoresis of FQ-resistant E. coli identified clonal spread of 1 strain among 16 residents. Loss (6 residents) or acquisition (7 residents) of FQ-resistant E. coli was documented and was associated with de novo colonization with genetically distinct strains. Unlike the case in the hospital setting, FQ-resistant E. coli carriage in long-term care facilities is associated with clonal spread.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1080-6040
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
889-94
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:15963284-Adult, pubmed-meshheading:15963284-Aged, pubmed-meshheading:15963284-Aged, 80 and over, pubmed-meshheading:15963284-Anti-Bacterial Agents, pubmed-meshheading:15963284-Carrier State, pubmed-meshheading:15963284-Colony Count, Microbial, pubmed-meshheading:15963284-Cross-Sectional Studies, pubmed-meshheading:15963284-Drug Resistance, Bacterial, pubmed-meshheading:15963284-Escherichia coli, pubmed-meshheading:15963284-Escherichia coli Infections, pubmed-meshheading:15963284-Feces, pubmed-meshheading:15963284-Female, pubmed-meshheading:15963284-Fluoroquinolones, pubmed-meshheading:15963284-Humans, pubmed-meshheading:15963284-Long-Term Care, pubmed-meshheading:15963284-Male, pubmed-meshheading:15963284-Microbial Sensitivity Tests, pubmed-meshheading:15963284-Middle Aged, pubmed-meshheading:15963284-Nursing Homes, pubmed-meshheading:15963284-Risk Factors
pubmed:year
2005
pubmed:articleTitle
Fluoroquinolone-resistant Escherichia coli carriage in long-term care facility.
pubmed:affiliation
Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA. joel.maslow@med.va.gov
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural