15963095

Source:http://linkedlifedata.com/resource/pubmed/id/15963095

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017431, umls-concept:C0050940, umls-concept:C0080103, umls-concept:C0085228, umls-concept:C0150312, umls-concept:C0743223, umls-concept:C1332828
pubmed:issue	1
pubmed:dateCreated	2005-6-20
pubmed:abstractText	Lansoprazole is affected by polymorphism of CYP2C19. The aim of this study was to examine the effects of fluvoxamine, a CYP2C19 inhibitor, on the pharmacokinetics of each lansoprazole enantiomer among three different CYP2C19 genotype groups.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/2-Pyridinylmethylsulfinylbenzimidazo..., http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C19 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Fluvoxamine, http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases, http://linkedlifedata.com/resource/pubmed/chemical/Omeprazole, http://linkedlifedata.com/resource/pubmed/chemical/lansoprazole
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	0306-5251
pubmed:author	pubmed-author:MiuraMasatomoM, pubmed-author:SugawaraKazunobuK, pubmed-author:SuzukiToshioT, pubmed-author:TadaHitoshiH, pubmed-author:TateishiTomonoriT, pubmed-author:UnoTsukasaT, pubmed-author:Yasui-FurukoriNorioN
pubmed:issnType	Print
pubmed:volume	60
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	61-8
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:15963095-2-Pyridinylmethylsulfinylbenzimidazoles, pubmed-meshheading:15963095-Adult, pubmed-meshheading:15963095-Area Under Curve, pubmed-meshheading:15963095-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:15963095-Cross-Over Studies, pubmed-meshheading:15963095-Double-Blind Method, pubmed-meshheading:15963095-Drug Interactions, pubmed-meshheading:15963095-Enzyme Inhibitors, pubmed-meshheading:15963095-Female, pubmed-meshheading:15963095-Fluvoxamine, pubmed-meshheading:15963095-Genotype, pubmed-meshheading:15963095-Humans, pubmed-meshheading:15963095-Male, pubmed-meshheading:15963095-Mixed Function Oxygenases, pubmed-meshheading:15963095-Omeprazole
pubmed:year	2005
pubmed:articleTitle	Enantioselective disposition of lansoprazole in relation to CYP2C19 genotypes in the presence of fluvoxamine.
pubmed:affiliation	Department of Pharmacy, Akita University Hospital, Akita, Japan.
pubmed:publicationType	Journal Article, Clinical Trial, Randomized Controlled Trial