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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
2
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pubmed:dateCreated |
2005-6-17
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pubmed:abstractText |
Successful immunological control of human immunodeficiency virus (HIV) infection is achieved only in rare individuals. Plasmacytoid dendritic cells (DCs) are mostly responsible for the production of strong antiviral factors--that is, type I interferons (IFNs)--in response to viruses. Their natural IFN production is impaired in chronic HIV infection, in correlation with viral load and disease progression, but it has not been tested during the critical stage of primary infection, when a balance is set between host immune responses and viral replication.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:DeveauChristianeC,
pubmed-author:DeveliogluLeylaL,
pubmed-author:GoujardCécileC,
pubmed-author:HosmalinAnneA,
pubmed-author:KahiSandrineS,
pubmed-author:KamgaIsabelleI,
pubmed-author:LebonPierreP,
pubmed-author:LichtnerMiriamM,
pubmed-author:MarañónConcepciónC,
pubmed-author:MeyerLaurenceL,
pubmed-author:SinetMartineM
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pubmed:issnType |
Print
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|
pubmed:day |
15
|
|
pubmed:volume |
192
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
303-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15962225-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:15962225-Adult,
pubmed-meshheading:15962225-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:15962225-Cohort Studies,
pubmed-meshheading:15962225-Dendritic Cells,
pubmed-meshheading:15962225-HIV Infections,
pubmed-meshheading:15962225-HIV-1,
pubmed-meshheading:15962225-Humans,
pubmed-meshheading:15962225-Interferon Type I,
pubmed-meshheading:15962225-Longitudinal Studies,
pubmed-meshheading:15962225-Middle Aged
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pubmed:year |
2005
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pubmed:articleTitle |
Type I interferon production is profoundly and transiently impaired in primary HIV-1 infection.
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pubmed:affiliation |
Institut Cochin, Département d'Immunologie, INSERM U567, Centre National de la Recherche Scientifique, UMR 8104, IFR 116, Université Paris V René Descartes, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
