|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1992-7-2
|
|
pubmed:abstractText |
The neuroanatomical substrate of seizures induced by picomolar amounts of corticotropin-releasing hormone in infant rats was investigated. Electrographic and behavioral phenomena were monitored in 42 rat pups aged 5 to 22 days. Rat pups carried bipolar electrodes implanted in subcortical limbic structures, as well as cortical electrodes and intracerebroventricular cannulae. The administration of corticotropin-releasing hormone produced age-specific seizures within minutes, which correlated with rhythmic amygdala discharges. Paroxysmal hippocampal and cortical discharges developed subsequently in some rats. Corticotropin-releasing hormone-induced electrographic and behavioral seizures originate in the amygdala.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-1685845,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-1700951,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-2073726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-2226617,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-2245800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-2783310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-2788078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-2846796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-3001239,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-3260555,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-3295587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-3871409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-4041021,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-6153342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-6267699,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-6314446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-6603889,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-6605787,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-7266871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1596084-7272738
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0364-5134
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
31
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
488-94
|
|
pubmed:dateRevised |
2011-9-13
|
|
pubmed:meshHeading |
pubmed-meshheading:1596084-Aging,
pubmed-meshheading:1596084-Amygdala,
pubmed-meshheading:1596084-Animals,
pubmed-meshheading:1596084-Animals, Newborn,
pubmed-meshheading:1596084-Behavior, Animal,
pubmed-meshheading:1596084-Corticotropin-Releasing Hormone,
pubmed-meshheading:1596084-Dose-Response Relationship, Drug,
pubmed-meshheading:1596084-Electroencephalography,
pubmed-meshheading:1596084-Electromyography,
pubmed-meshheading:1596084-Jaw,
pubmed-meshheading:1596084-Myoclonus,
pubmed-meshheading:1596084-Rats,
pubmed-meshheading:1596084-Rats, Inbred Strains,
pubmed-meshheading:1596084-Seizures,
pubmed-meshheading:1596084-Stereotyped Behavior
|
|
pubmed:year |
1992
|
|
pubmed:articleTitle |
Corticotropin-releasing hormone-induced seizures in infant rats originate in the amygdala.
|
|
pubmed:affiliation |
Department of Neurology, University of Southern California, Los Angeles.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
